SONICA® CL4% Concentrated Aqueous Disinfectant
Ultrasonic Liquid CL4%
Ultrasonic Cleaners Datasheet
How to use
Namesort iconphDilution in water %Bath Cleaning temperature
AC2.5010-1050
AF0.005-1040
CL4%7.002-430
DW10-0
ML10.005-1065
PCB11.000-040
RC13.000-060
RG8.000-040
SF13.008-1060
UG7.005-1040
Winch Clean 17.001-1060
Winch Clean 214.005-1070
Compatibility
Namesort iconAlluminiumSteelBrassCopper
AC1444
AF0211
CL4%4555
DW15555
ML5555
PCB2534
RC0522
RG5555
SF0522
UG5555
Winch Clean 15555
Winch Clean 20522
Residuals removal
Namesort iconOilGreaseOxideLimestonePlasterAlginateCementWaterOrganic residues
AC113300003
AF225500003
CL4%210000005
DW1000000050
ML542000004
PCB222000004
RC320000504
RG000054002
SF321000504
UG411000004
Winch Clean 1320000004
Winch Clean 2551000004
Properties
Namesort iconDewatering and coatingDescaleDetergentDisinfectant
AC0430
AF0520
CL4%0045
DW15000
ML0050
PCB0040
RC0500
RG0510
SF0040
UG0040
Winch Clean 10050
Winch Clean 20030

Ultrasonic Cleaner liquid CL4%

Concentrated Disinfectant Aqueous Solution for medical devices particulary suitable for SONICA decontamination tank and SONICA® ultrasonic cleaners.

Application Fields

  • Decontamination and simultaneous detergency of surgical instruments and medical devices
  • Temporary sterile conservation of surgical instruments

Action Mechanism

Chlorexidine reacts with the negatively charged groups that are found on the cell surface.
For this reason, when it comes into contact with bacterial suspensions, it is absorbed immediately, causing an irreversible loss of cytoplasm components, which damages the cell membrane and inhibits enzymes. Cetrimide is a quaternary ammonium salt that reduces surface tension in the point of contact and has precipitant, complexing and denaturing effects on bacteria proteins, causing enzyme changes in the cytoplasm membrane.

Germicidal Activity

Chlorexidine acts on vegetative bacteria, yeasts, fungi, several protozoa, viruses (HIV) and salmonella. Cetrimide acts as a bactericide above all on gram-positive bacteria; it has varying fungistat properties and acts as a virucide against lipophilic viruses. The action of the product is superior to that of its single components.
Its bactericidal actions are reduced by the presence of organic material (serum).
In hospital usage SONICA® CL4% is mainly recommended for its action against gram-negative and gram-positive bacteria, as well as lipophilic viruses (HIV).
From the tests made, SONICA® CL4% has shown that it acts against such bacteria as Citrobacter freundi, Serratia marcescens, Pseudomonas aeruginosa ATCC 15442, Pseudomonas aeruginosa ATCC 14502, Proteus rettgeri, Staphylococcus aureus ATCC 114, Staphylococcus aureus ATCC 6538, and Klebsiella pneumoniae.

Research

The efficiency of a decontamination procedure by sonication for different dental instruments after experimental microbial and viral contamination was tested.
Both germicidal and virucidal activity of sonication in presence or absence of a cationic bio-biguanid disinfectant was assessed following three different disinfection/sterilisation protocols.
Dental instruments were contaminated with a mixed culture of Streptococcus faecium, Staphylococcus sp., Pseudomonas aeruginosa, Mycobacterium sp., Escherichia coli and Bacillus subtilis, or with Polio virus type 1 and Herpesvirus simplex type 1 (HHV1, following the new herpesvirus denomination), exposed to ultrasonic treatment in an ultrasonic bath and the surviving microorganisms titered.
The results showed that an effective disinfection of dental instruments, expressed by an equal or higher than 4 logs microbial and viral reduction, can be obtained after 15 min or 10 min sonication in the ultrasonic cleaner equipped with a Sweep System Technology. Conversely, by the combined action of chemical disinfection and ultrasonic treatment in the same device, a sterilising effect was obtained after only 5 min for microbial and after 10-15 min for virally contaminated instruments.
The synergistic effect of chemical and physical means, as already accepted as an effective cleaning procedure of medical instruments, can therefore be applied to obtain a safe and effective sterilisation of dental instruments potentially contaminated by organic fluids and dental material harbouring pathogenic microbes and viruses.

Authors:
*Patrizia Di Gennaro, *Giuseppina Bestetti, °Antonia Radaelli, §Manuela Paganini, §Carlo De Giuli Morghen, §Margherita Neri
*Department of Environmental Sciences, University of Milano-Bicocca, 20126 Milano, Italy.
Departments of §Medical Pharmacology and °Pharmacological Sciences, University of Milano, 20129 Milano, Italy.
Corresponding author: Prof. Giuseppina Bestetti, Department of Environmental Sciences, University of Milano-Bicocca, P.zza della Scienza, 1 20126 Milano Italy, Phone: 0039-2-64482925; Fax: 0039-2-64482996; E-mail: Giuseppina.Bestetti@unimib.it

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